主题：国际最新研究成果，茶树油在口腔护理用品的疗效确切

The essential oil of Melaleuca alternifolia has a similar antimicrobial activity to that of chlorhexidine, although their mechanisms of action differ. A main component of the oil, 1,8-cineole, has additional anti-inflammatory properties. It was thought that tea tree oil may have therapeutic potential in the treatment of chronic gingivitis and periodontitis as both conditions have bacterial and inflammatory components. An Australian duo performed a double-blind, longitudinal non-crossover trial using 49 subjects with moderate to severe gingivitis, divided into three groups. The test group applied a gel containing 2.5% tea tree oil with a tooth brush, the positive control group used a 0.2% chlorhexidine gel and the negative control a placebo gel. The study lasted eight weeks and the Gingival Index (GI), Papillary Bleeding Index (PBI) and the Plaque Surface Score (PSS) were measured at 0, four and eight weeks. The subjects were instructed to use the gel as a dentifrice, making sure it was in contact with the gingival tissues adjacent to the teeth for a minimum of 2 min twice daily. For 30 min post application no eating, drinking or rinsing was allowed and no other proprietary toothpastes, mouthwashes or other cleaning aids were permitted during the duration of the study. The results were separated into anterior/posterior teeth and buccal/lingual tooth surfaces. The tea tree oil group demonstrated significant reduction in PBI and GI scores, but did not reduce plaque scores, which tended to increase during the latter weeks of the study period. Generally, the chlorhexidine group showed more improvements in PSS than the other groups and had the greatest reduction in plaque scores. There were no adverse reactions to any of the gels. The potent antibacterial activity of tea tree oil in vitro did not translate to a similar result in vivo, as decreased gingival inflammation occurred without a concomitant decrease in plaque scores. The beneficial effects of M. alternifolia essential oil were thus ascribed to its anti-inflammatory properties and it was postulated that it may be a useful addition to the current range of periodontal treatment options.

谢谢!

buhaoyisi

楼主既然有心贴过来，何不顺便翻译一下。

我来翻译一下：

The essential oil of Melaleuca alternifolia has a similar antimicrobial activity to that of chlorhexidine, although their mechanisms of action differ. A main component of the oil, 1,8-cineole, has additional anti-inflammatory properties. It was thought that tea tree oil may have therapeutic potential in the treatment of chronic gingivitis and periodontitis as both conditions have bacterial and inflammatory components.
An Australian duo performed a double-blind, longitudinal non-crossover trial using 49 subjects with moderate to severe gingivitis, divided into three groups. The test group applied a gel containing 2.5% tea tree oil with a tooth brush, the positive control group used a 0.2% chlorhexidine gel and the negative control a placebo gel. The study lasted eight weeks and the Gingival Index (GI), Papillary Bleeding Index (PBI) and the Plaque Surface Score (PSS) were measured at 0, four and eight weeks.
The subjects were instructed to use the gel as a dentifrice, making sure it was in contact with the gingival tissues adjacent to the teeth for a minimum of 2 min twice daily. For 30 min post application no eating, drinking or rinsing was allowed and no other proprietary toothpastes, mouthwashes or other cleaning aids were permitted during the duration of the study.
The results were separated into anterior/posterior teeth and buccal/lingual tooth surfaces. The tea tree oil group demonstrated significant reduction in PBI and GI scores, but did not reduce plaque scores, which tended to increase during the latter weeks of the study period. Generally, the chlorhexidine group showed more improvements in PSS than the other groups and had the greatest reduction in plaque scores. There were no adverse reactions to any of the gels.
The potent antibacterial activity of tea tree oil in vitro did not translate to a similar result in vivo, as decreased gingival inflammation occurred without a concomitant decrease in plaque scores. The beneficial effects of M. alternifolia essential oil were thus ascribed to its anti-inflammatory properties and it was postulated that it may be a useful addition to the current range of periodontal treatment options.

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茶树精油有类似于氯己定（一种医用广谱抑菌防腐消毒药物）的抗菌作用，虽然二者作用机制不同。1,8-桉叶素，是茶树精油的主要成分之一，具有消炎作用。过去人们已经认识到茶树精油在治疗细菌引起的慢性牙龈炎以及牙周炎方面的疗效。

两位澳大利亚研究者曾做过这样一个实验，在患者不知情的情况下，随机将49个患有不同程度牙龈炎的患者分成3组，分别让他们使用三种不同的膏状制剂，甲组用2.5％浓度的茶树油，乙组用0.2％浓度的氯己定，而丙组则用一种不含任何药性的制剂。该实验持续了8周，并分别在一开始、第四周和第八周时记录受试者的牙龈问题指数（GI），牙龈出血指数（PBI）和表面牙菌斑（PSS）。

让受试者将这些制剂当作牙膏刷牙，每天两次，每次至少两分钟。并告诉他们这些制剂均是针对牙龈问题的药物，而且在刷牙后30分钟内禁止饮食或漱口。当然在实验期间，也不允许使用其他自备的牙膏、漱口水或其他口腔清洁用品。

测试结果按照牙齿的前后位置，以及内外两面单独分开。结果甲组（使用茶树油的那组）受试者的牙龈和出血问题（GI和PBI）显著减轻，只有牙菌斑得分（PSS）未降低，且在剩余几周内有上升趋势。乙组（使用氯己定的）的受试者大部分牙菌斑指数（PSS）较之其他两组有明显改进，牙菌斑指数减低最大。另外，三组均未见不良反应。

茶树精油在生物体外的有效抗菌活动，不意味着在生物有机体内也有同样功效。例如在减轻牙龈发炎的同时，不能降低牙菌斑指数。茶树精油对口腔的益处在于它可以消除炎症，并在牙周疾病的治疗中，作为有限范围内的有效辅助物之一。

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其中我将 Plaque 这个字翻译成“牙菌斑”，因为我查了一份美国牙科联合会的口腔专业英语词汇，里面对 Plaque 的解释是 A soft sticky substance that accumulates on teeth composed largely of bacteria and bacterial derivatives.（附着在牙齿表面的粘性物，由细菌和细菌衍生物组成）

还没开始学习茶树油的功效

译文很精彩，辛苦了！

希望更多的人分享芳香疗法领域的新进展。

可以把茶树经由滴在漱口水里把

good

不知道对稚齿有没有作用。